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Dr Johanna Feary

Laboratory animal allergy is preventable in modern research facilities

Article
We surveyed 750 laboratory animal workers and measured airborne Mus m 1 (mouse allergen) levels in seven UK institutions. We compared the prevalence of sensitisation to mouse proteins (by specific IgE assay or skin prick test) and of work-related allergic symptoms in IVC-only and open cage units.

Occupational contributions to Interstitial Lung Disease

Editorial
  • Globally, coal workers pneumoconiosis, silicosis, and asbestosis remain the most important pneumoconioses.
  • Idiopathic pulmonary fibrosis (IPF) and asbestosis can be challenging to differentiate clinically, and there is clear evidence for an occupational contribution to IPF.
  • Bacterial contamination of metal working fluid has recently emerged as an important cause of occupational hypersensitivity pneumonitis.

Occupational exposure to particulate matter and staff sickness absence on the London underground

Article

The London Underground (LU) employs over 19,000 staff, some of whom are exposed to elevated concentrations of particulate matter (PM) within the network. This study quantified the occupational exposure of LU staff to subway PM and investigated the possible association with sickness absence (SA).

A job exposure matrix to quantify subway PM2.5 staff exposure was developed by undertaking measurement campaigns across the LU network. The association between exposure and SA was evaluated using zero-inflated mixed-effects negative binomial models.

Occupational exposures and small airway obstruction in the UK Biobank Cohort

Article

Background

Small airways obstruction (SAO) is a key feature of both COPD and asthma, which have been associated with workplace exposures. Whether SAO, which may occur early in the development of obstructive lung disease and without symptoms, also associates with occupational exposures is unknown.

Methods

Occupational lung disease: when should I think of it and why is it important?

Article

Exposure to toxic inhalants in the workplace has the potential to cause (in susceptible individuals) almost any major type of lung disease, such as asthma, COPD and interstitial lung diseases. Patients with occupational lung disease will often present to or will be managed by respiratory specialists without training in occupational respiratory medicine, and patients (or their clinicians) may not identify a link between their disease and their current or a past job.